Prevalence of anti A and anti B titer among blood group O donors

Authors

  • Alia Maisarah Mohd Azli
  • Mazura Bahari FSK UiTM Selangor Puncak Alam Campus

Keywords:

Blood, Group O, Anti A, Anti B, Transfusion

Abstract

Blood group O is well known as universal donors. However, some of the antibodies from group O, which are anti A and anti B may able to cause hemolysis of recipient’s red blood cells if it is presented in sufficient high titer. Therefore, this pilot study was conducted to determine the prevalence of anti A and anti B titer among the blood group O donors. This study was carried out on 30 test tubes of blood, originated from leftover samples. All the samples from blood group O donors had been chosen randomly. Anti A and anti B antibody titration using the conventional tube technique had been done. Pearson Chi-square and Fisher’s Exact test was used to compare the association between titration value and types of antibodies. This study showed that the prevalence of anti A and anti B titer among blood group O donors is 90.0% at the titer lower than 128. The critical value of ‘high-titer’ is also at the titer lower than 128. The result showed that there is no significance association between titration value and types of antibodies (p > 0.05). In conclusion, the blood group O donors can be accepted as the universal donors and can be released as safe O when the titer is lower than 128.

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Published

2021-10-30

How to Cite

Mohd Azli, A. M., & Bahari, M. (2021). Prevalence of anti A and anti B titer among blood group O donors. Healthscope: The Official Research Book of Faculty of Health Sciences, UiTM, 4(1), 94-98. Retrieved from http://healthscopefsk.com/index.php/research/article/view/221

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Section

Articles